Re: Očkování proti neštovicím

Terinko,
sice to nebylo na me, ale pokusim se. Nejvice evidence lze ziskat z USA, kde se proti planym nestovicim zacalo plosne ockovat v roce 1995. Prvnich 5 let se zdalo, ze vse je na nejlepsi ceste, ubylo hospitalizovanych deti. Jenze pak se ukazalo, ze se vlastne musi dat jeste booster, u ktereho stejne nikdo nevi, jak dlouhou ucinnost bude mit. Planovane jsou i boostery pro dospele. A druha vec je, ze pokud nestovice ve spolecnosti prirozene koluji, pak kazdy clovek si po kazdem setkani s nimi prirozene zvysuje imunitu. Plati to i pro dospele. Bylo zaznamenano, ze pediatri pracujici s detmi trpi na pasovy opar v pomeru s beznou populaci o polovinu mene (uvadi se az 7/8 mene). Setkavani se s timto virusem je tedy vseobecne prospesne pro celou populaci.

While 73 percent of the youngsters who became ill in 1995 were under age 7, the rate dropped to 30 percent by 2004 because the children who got chickenpox were older.

And when vaccinated children were infected, they tended to be sicker, probably because they were older. “Children between the ages of 8 and 12 years who had been vaccinated five years or more previously were two times as likely to have moderate-to-severe breakthrough disease as were those who had been vaccinated less than five years previously,” the researchers wrote.

Zatimco v roce 1995 bylo 70% deti,ktere onemocnely, vekove pod 7 let, v roce 2004 to bylo pouze 30%, protoze deti, ktere onemocnely, byly celkove starsi.
A kdyz byly infikovane starsi ockovane deti, prubeh nemoci byl vaznejsi. U deti ve veku 8-12 let, ktere byly ockovane pred vice nez 5ti lety, byla pravdepodobnost stredniho az tezkeho prubehu nemoci dvakrat vyssi nez u deti, ktere byly ockovane pred mene nez 5ti lety.

A second dose would provide extra protection, but it is not clear how much. (Dr. Seward, the acting deputy director of the centers’ division of viral diseases.)
Druha davka by mela zajistit vetsi ochranu, ale neni jiste, jak presne velkou.

No one knows how long the effects of a second shot would last, said the research team, led by Dr. Sandra Chaves of the C.D.C.
Nikdo nevi, jak dlouho potrva ochrana druhe davky...

“Because the vaccine is eliminating chickenpox disease, children and adults no longer receive the natural boost to their immune systems that they received from periodic exposures to the disease,” says Gary S. Goldman, Ph.D., author of the study and former research analyst with VASP. “Due to the dramatic decline in chickenpox, children are now experiencing a higher incidence of shingles.
Studie rika, ze jelikoz vakcina eliminuje nestovice, deti a dospeli nejsou jiz vystaveni prirozenemu boosteru jejich imunitniho systemu, ktereho se jim dostavalo setkavanim se s timto onemocnenim, rika Gary S. Goldman, PhD, autor studie... Diky dramatickemu snizeni vyskytu nestovic se nyni u deti mnohem casteji objevuje pasovy opar. (Pasovy opar se drive u deti nevyskytoval, spise u starsich dospelych)

To compensate for this, vaccine manufacturers plan to license a booster "shingles" vaccine to substitute for the natural boost in immunity that occurred when chickenpox disease was previously circulating in the population. Goldman expresses doubts about the effectiveness of this approach to the impending problem.
Aby se toto kompensovalo, vyrobci vakcin planuji licenci na booster proti pasovemu oparu, jako nahrazku za prirozeny boost imunity, ktery se vyskytuje pri setkani se s nestovicemi. Goldman vyjadruje pochybnosti o efektivnosti tohoto pristupu.

Mmch pro ockovane deti jsou planovane boostery pro starsi deti, pro adolescenty a pak i pro dospele. Takze pokud nechate dite naockovat a chcete mu udrzet imunitu proti nestovicim, tak to vypada, ze se bude muset nechavat preockovat do nekonecna...
Napr dospeli, kteri maji deti, maji mnohem mensi pravdepodobnost, ze chytnou pasovy opar, ve srovnani s bezdetnymi dospelymi. Ovsem jak to bude do budoucna, pokud se rozhodneme nestovice eradikovat, tot otazka.